Evers ES, et al. – This study analyzed the correlations between postoperative heart-type fatty acid-binding protein (H-FABP), creatine kinase–myocardial band (CK–MB), troponin–I, total bypass time, and clinical outcomes in pediatric cardiac surgery patients. For prognosis prediction in pediatric cardiac surgery patients, the predictive value of H–FABP was not stronger than that of CK–MB, Troponin–I, or bypass times.

Methods

• Researchers measured H-FABP, troponin-I and CK-MB preoperatively and 1, 3, and 6 h after aortic declamping in 32 pediatric patients that underwent ventricular septal defect closure.
• They calculated Spearman's Rho correlations between laboratory and clinical parameters including inotropic support duration, aortic cross-clamp time, total bypass time, ventilation.weaning.time, and total Intensive Care Unit stay.

Results

• Findings demonstrated that H-FABP, CK-MB, troponin-I, and total bypass time had a similarly weak to moderate correlation with clinical outcome measures.