Does diabetes impact therapeutic immunomodulation therapy decisions for kidney transplant recipients? Data from the Folic Acid for Vascular Outcome Reduction in Transplant (FAVORIT) trial
International Journal of Nephrology and Renovascular Disease Aug 31, 2017
Weinrauch LA, et al. – Hypothesthesis stating that among stable kidney transplant recipients, there might be differences between subgroups with and without diabetes with respect to prevalence of prior cardiovascular events and post–transplant antihypertensive and immunosuppressive therapy, has been tested. A greater prevalence of prior cardiovascular events is observed in recipients with diabetes. These patients are more likely to have required multiple medications to control hypertension and are more likely to have received tacrolimus as opposed to cyclosporine than the non–diabetic transplant recipients (all p<0.001). These outcomes call for further exploration of the effect of differences in treatment of non–diabetic vs diabetic cohorts after stable renal transplantation upon outcomes, it can provide additional information that might lead to improved care.
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