de Camargo Smolarek P, et al. - Experts aspired to explore whether pain and disruptive behavior can be reduced by the use of computerized local dental anesthesia in children. To choose randomized clinical trials that compared computerized and conventional anesthesia, the literature was screened. Only studies classified as "low" or "unclear" risk in the key domains at study level were involved for the meta-analysis. According to this systematic review and meta-analysis, pain perception and disruptive behavior in children with computerized or conventional dental local anesthesia do not vary. The quality of the available evidence, however, is poor.