Hosseininejad SM, et al. - In patients with renal colic, researchers compared the effectiveness of ultra-low-dose intravenous (IV) naloxone combined with IV morphine vs IV morphine alone for reducing pain and morphine-induced side effects via a double-blind clinical trial with 150 patients aged 34 to 60?years old presenting to the emergency department (ED) with renal colic. Better analgesia and sedation/agitation states were not evident among patients provided co-treatment of ultra-low-dose naloxone with morphine vs those who only received IV morphine.