Nystrom CD, et al. - Differences in cardiometabolic risk and HOMA of insulin resistance (HOMA-IR) across BMI categories (underweight to morbid obesity) were examined. In addition, the authors aimed to investigate whether fit children had lower cardiometabolic risk/HOMA-IR than unfit children in each BMI category and to explore differences in cardiometabolic risk/HOMA-IR in normal-weight unfit children and obese fit children. BMI categories rose along with cardiometabolic risk and HOMA-IR. This underscored the need for obesity prevention/treatment programs in childhood. Moreover, in lowering the risk of cardiometabolic diseases in obese children, cardiorespiratory fitness (CRF) could play an important role.