Qiu Q, Huang J, Li Y, et al. - Researchers here examined if IVF/ICSI outcomes could be improved with an artificially induced FSH surge at the time of hCG trigger. They conducted a randomized, double-blinded, placebo-controlled trial at a single IVF center, from June 2012 to November 2013. They enrolled patients aged ≤ 42 years who were treated with IVF/ICSI owing to tubal factor, male factor, unexplained, endometriosis and multiple factors. Participants were provided a standard long GnRH agonist (GnRHa) protocol for IVF/ICSI and hCG 6000–10 000 IU to trigger oocyte maturation. They performed randomization of a total of 364 and 368 patients to receive a urinary FSH bolus (6 ampules, 450 IU) and placebo, respectively, at the time of the hCG trigger. Outcomes revealed no effect of an additional FSH bolus administered at the time of hCG trigger on clinical pregnancy rate, embryo quality, fertilization rate, implantation rate and live birth rate in women undergoing the long GnRHa protocol for IVF/ICSI.