Zorio V, Lebreton T, Desgranges FP, et al. - In this study with children scheduled for surgery under general anesthesia, researchers assessed the ability of a 3 mL kg⁻¹ mini‐fluid challenge over 2 minutes to predict fluid responsiveness in pediatric population under controlled ventilation. Participants received a fluid challenge of 15 mL kg⁻¹ of crystalloid before incision given over 10 minutes in two steps: 3 mL kg⁻¹ over 2 minutes then 12 mL kg⁻¹ over 8 minutes. An alteration of ≥10% in cardiac output estimated by left ventricular outflow tract velocity time integral (VTI) as determined by transthoracic ultrasound prior to and following the fluid challenge of 15 mL kg⁻¹, defined fluid responsiveness. Of 55 patients included, fluid responders were 43. Findings revealed that in anesthetized children under controlled mechanical ventilation, the impacts of a fluid challenge of 15 mL kg⁻¹ of crystalloid were weakly predicted by ΔVTI_miniFC (rise in the VTI following the mini‐fluid challenge).