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Does a hypnosis session reduce the required propofol dose during closed-loop anaesthesia induction?: A randomised controlled trial

European Journal of Anaesthesiology Aug 09, 2018

Bataille A, et al. - Given hypnosis has a positive effect on peri-operative anxiety and pain, researchers performed this 1 : 1 randomised, usual-care-controlled, single-centre trial to evaluate the effect of a formal deep hypnosis session on the consumption of propofol for anaesthetic induction using automated administration of propofol guided by the bispectral index (BIS) in a closed loop. Participants were female adult patients scheduled for outpatient gynaecological surgery under general anaesthesia. These patients were randomised to receive either a deep hypnosis session or routine care prior to surgery. The main emphasis was laid on the propofol dose required for anaesthesia induction, defined as a BIS less than 60 for at least 30 s. Analysis of 31 patients in the hypnosis group and 35 in the control group revealed no evidence of a difference in the mean required propofol dose for anaesthetic induction between the hypnosis and the control groups (2.06 mg kg-1 vs 1.79 mg kg-1, respectively).
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