Do ultrathin strut bare-metal stents with passive coating improve efficacy in large coronary arteries?: Insights from the randomized, multicenter BASKET-PROVE trials
BMC Cardiovascular Disorders Oct 23, 2019
Hansen KW, Jeger R, Sørensen R, et al. - Given higher rates of symptomatic restenosis in patients receiving the newer generation bare-metal stents (BMS) have been reported in smaller studies, researchers compared a newer generation ultrathin strut silicon-carbide coated cobalt-chromium (CoCr) BMS (SCC-BMS) vs an older thin-strut uncoated CoCr BMS (UC-BMS) for efficacy in patients having coronary artery disease needing stenting of large vessels (≥ 3.0 mm). Participants were all patients randomized to SCC- (n = 761) or UC-BMS (n = 765) in the two BAsel Stent Kosten-Effektivitäts Trial-PROspective Validation Examination (BASKET-PROVE) trials. They found a higher risk of clinically driven repeat revascularization in relation to the use of the newer generation SCC-BMS vs the UC-BMS, with no signs of an offsetting safety advantage, in patients needing stenting of large coronary arteries.
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