Clark CL, et al. - Researchers sought to determine the association of high-sensitivity troponin (hscTnT) and Natriuretic Peptide (NT-proBNP), drawn in the Emergency Department (ED), with 30-day death/ serious cardiac outcomes in adult patients presenting with syncope. They conducted a pre-specified secondary analysis of a prospective, observational trial enrolling participants ≥ age 60 presenting with syncope, at 11 United States hospitals, between 4/2013 and 9/2016. The cohort included 3,392 patients; 367 (10.8%) experienced the primary outcome of combined 30-day all-cause mortality and serious cardiac events. Adjusted absolute risk for the primary outcome increased with hscTnT and NT-proBNP levels. This suggests the independent predictive value of HscTnT and NT-proBNP for 30-day death and serious outcomes in older ED patients presenting with syncope.