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Do ground-glass opacity-dominant features have prognostic significance in node-negative adenocarcinomas with invasive components of similar sizes?

European Journal of Cardio-Thoracic Surgery Feb 19, 2020

Han SJ, Jeon JH, Jung W, et al. - Researchers investigated the significance of the dominant features of ground-glass opacities (GGOs) in the prognosis of part-solid node-negative adenocarcinomas with invasive components of similar sizes. They picked a total of 544 patients with a diagnosis of part-solid pathological node-negative adenocarcinoma with an invasive component < 20 mm in size from 2004 to 2017. Following propensity score matching, 92 patients in each group were selected for the prognostic analysis. The solid part had the mean size of 8.8 mm in the GGO-dominant group and 9.0 mm in the solid-dominant group; the mean size of the total lesion was 22.2 mm in the GGO-dominant group and 14.9 mm in the solid-dominant group. Although the total sizes of the GGO-dominant lesions vs the solid-dominant lesions were larger, no significant difference was observed in the prognosis of patients with GGO-dominant lesions vs patients with solid-dominant lesions in node-negative adenocarcinomas with a similar invasive component size < 20 mm
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