Rahdar HA, et al. - Researchers investigated the presence of Brucella melitensis and Brucella abortus genomes in the synovial fluid (SF) samples from 90 patients with rheumatoid arthritis (RA). Of these, 14 were positive for B. melitensis (n=9) and B. abortus (n=5). In all 9 samples of B. melitensis, the virB, cbg, and om31 were detected. Of the five B. abortus-positive samples, zhuA and manA were detected in three (60%) and four (80%), respectively. Findings thus suggested that in the SF of RA patients, the Brucella spp. genomes could be detected by the PCR-based method. Physicians are hence recommended considering the Brucella spp. as indicators of potential RA for the timely diagnosis and treatment of RA.