Wang F, et al. - Individuals with multiple pituitary hormone deficiencies (MPHD, n = 184) were classified into four groups according to their MRI results ie, pituitary stalk interruption syndrome (PSIS, n = 93), hypoplasia (n = 24), normal (n = 10), and tumor survivor (n = 57) in order to investigate the hormone profiles of Chinese children and adolescents with various MPHD etiologies. Among children and adolescents with MPHD, a high frequency of PSIS was noted. moreover, in individuals with MPHD, in comparison with the other groups, the severity of hormone deficiencies was more significant in the tumor survivor group.