Tisherman RT, Hankins ML, Moloney GB, et al. - Researchers assumed that unlocked nails will indicate elevated varus collapse and inferior construct stiffness in specimens with increased diaphyseal medullary diameter. Sixteen non-cadaveric osteoporotic biomechanical femur specimens were utilized in this study, with eight specimens having an artificially large femoral canal to represent Dorr C femurs. The data exhibited that for unstable peritrochanteric fractures, unlocked short intramedullary fixation results in increased varus collapse under axial compression. For unstable peritrochanteric fractures, this research supports the use of distal cross-locking of short intramedullary fixation in patients with capacious femoral canals secondary to osteoporosis who might otherwise be at risk for varus collapse, device failure, and malunion.