Disparities in care among patients with low-grade serous ovarian carcinoma
Gynecologic Oncology Feb 09, 2020
Siemon J, et al. - Given there is little data on the impact of sociodemographic factors on diagnosis and results in low-grade serous carcinoma (LGSC; a rare histotype of ovarian cancer), so, researchers used the National Cancer Database to assess the links between these factors and the clinical features, treatment approaches, and survival in LGSC. Overall 3,221 patients were analyzed, of those, 89.5% were White, 6.2% were Black; 7.2% were Hispanic, 92.8% were non-Hispanic. In Blacks vs Whites, younger age at diagnosis, less receipt of chemotherapy, and less elevation of CA-125 were noted. Younger age at diagnosis and less receipt of chemotherapy were also noted among Hispanics vs non-Hispanics. Higher 30-day mortality related to government insurance vs private insurance was reported. OS was not predicted by race/ethnicity, but an independent link with worse OS was displayed by older age, advanced stage, and government insurance. Overall, findings show that clinical features, treatments, and results of LGSC vary significantly by sociodemographics.
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