Disease damage influences cardiovascular risk reclassification based on carotid ultrasound in patients with systemic lupus erythematosus
The Journal of Rheumatology May 04, 2019
Quevedo-Abeledo JC, et al. - Carotid artery ultrasound (US) can help find high-risk cardiovascular (CV) patients with inflammatory arthritis, so researchers evaluated how CV risk stratification of systemic lupus erythematosus (SLE) patients is influenced by carotid US assessments. Study participants were 276 patients with SLE. In order to assess how risk reclassification was influenced by disease characteristics in patients with SLE, a multivariable regression analysis was performed, adjusted for classic CV-related factors. Age, disease duration, presence of hypertension, Systemic Lupus International Collaborating Clinics > 0, waist circumference, and C3 and triglyceride serum levels were included in a predictive reclassification model. Following carotid US assessments in patients with SLE, reclassification into a very high-risk category is common according to this cross-sectional study, and this is influenced independently by disease damage.
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