Callhoff J, Albrecht K, Redeker I, et al. - From a random sample of 8,995 people with OA from a German statutory health insurance (3,564 finished a survey including the Western Ontario and McMaster Universities Osteoarthritis Index [WOMAC]), researchers assessed factors related to the burden of OA, considering the pattern of joint involvement. Individuals with knee (n = 1,448), hip (n = 959), knee and hip (n = 399) or polyarthritic (n = 758) OA were involved. Concomitant knee and hip OA was concurrent with the highest WOMAC values, frequent impairment of personal life and the highest use of analgesics. In the regression analyses, despite the joint manifestations, BMI per 5 units and WHO-5 per 10% worsening were related to a rise in WOMAC values of 4-5 points. Hence, in individuals with concomitant knee and hip OA, disease burden is high, going along with frequent prescription of analgesics. While using the WOMAC as an outcome instrument, involvement of several joints, BMI and depressive symptoms are required to be recognized.