Vilaca T, et al. - Researchers performed a systematic review and meta-analysis on the risk of ankle and wrist fractures in diabetes to gauge whether there is a clinical consequence for peripheral microarchitectural abnormalities often described in these patients. In diabetes, the risk of fractures is increased at the ankle and decreased at the wrist. Experts observed the same pattern in obesity. In obesity and diabetes, bone microarchitectural features are different, but in both the diseases, epidemiology of peripheral fractures is similar, suggesting that, in these populations, microarchitecture might not be a major factor for peripheral fractures.