Fang J, et al. - In this retrospective study, the incidence and risk factors for hepatitis B virus (HBV) reactivation was assessed among 105 hepatitis B surface antigen (HBsAg)-positive patients under immunotherapy for glomerulonephritis. Among completion, discontinuation, and rejection of antiviral prophylaxis, a significant difference was noted with respect to HBV reactivation. Discontinuation of antiviral prophylaxis was shown to increase the risk of HBV reactivation. Baseline HBV DNA detectable and discontinuation of antiviral prophylaxis were suggested as two independent risk factors for HBV reactivation in the univariate and multivariate analysis.