Akhter T, Wikström G, Larsson M. et al, et al. - Elevation in asymmetric- and symmetric dimethylarginines (ADMA, SDMA) has been observed in cardiovascular disease (CVD). Researchers here examined if in women with and without preeclampsia, arterial wall layer dimensions and cardiovascular risk factors are associated with ADMA, SDMA levels and L-arginine/ADMA and L-arginine/SDMA ratios during pregnancy and their changes from pregnancy to postpartum. They analyzed dimethylarginines by LC-MS, and the common-carotid-artery (CCA) intima and determined media thicknesses using 22-MHz non-invasive ultrasonography in women with preeclampsia (cases = 48) and normal pregnancies (controls = 58) in similar gestational age, with reassessment 1-year postpartum. Findings support the correlation of dimethylarginines with signs of adverse effects on arterial wall layer dimensions and cardiovascular risk factors in women with and without preeclampsia, during pregnancy and with their alterations from pregnancy up to 1-year postpartum.