Hempel JM, et al. - A total of 77 subjects were retrospectively evaluated between August 2013 and October 2017 to estimate the predictive ability of preoperatively evaluated diffusion kurtosis imaging (DKI) metrics as prognostic factors in the 2016 World Health Organization Classification of Tumors of the Central Nervous System integrated glioma groups. Investigators used mean kurtosis (MK) and mean diffusivity (MD) histogram parameters from DKI, overall and progression-free survival, and relevant prognostic molecular data (isocitrate dehydrogenase [IDH]; alpha-thalassemia/mental retardation syndrome X-linked [ATRX]; chromosome 1p/19q loss of heterozygosity). They observed age of patient and MK from DKI suitable for predicting overall and progression-free survival preoperatively. The molecular subgroups appeared to be prognostic in gliomas with ATRX retention, denoting a feature of IDH wild-type gliomas.