Differentiation of glioblastoma and solitary brain metastasis by gradient of relative cerebral blood volume in the peritumoral brain zone derived from dynamic susceptibility contrast perfusion magnetic resonance imaging
Journal of Computer Assisted Tomography Jan 25, 2019
She D, et al. - Among 43 patients with a solitary brain tumor, researchers assessed the effectiveness of the relative cerebral blood volume (rCBV) gradient in the peritumoral brain zone (PBZ)—the difference in the rCBV values from the area closest to the enhancing lesion to the area closest to the healthy white matter—in differentiating glioblastoma (GB) from solitary brain metastasis (MET). Using the nonparametric Mann-Whitney test, the perfusion parameters were evaluated. According to the findings, the rCBV gradient parameter derived from dynamic susceptibility contrast perfusion MRI (DSC-MRI) in the PBZ appears to be the most effective parameter for distinguishing GB from METs.
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