Franz D, et al. - In this prospective study of 21 healthy subjects, researchers mitigated issues of current T₂*-measurement techniques through experimental design and examined gluteal and supraclavicular adipose tissue (AT) T₂* and proton density fat fraction (PDFF) and their relationship using a 20-echo gradient-echo acquisition. Data reported that PDFF and T₂* differed significantly between supraclavicular and gluteal AT with 6 and 20 echoes. According to findings, an increase in the number of echoes sampled beyond 6 does not affect AT PDFF quantification, whereas AT T₂* is significantly affected. A 20-echo gradient-echo acquisition, therefore, enables multiparametric analysis of both AT PDFF and T₂* and can thus improve MR-based differentiation between white and brown fat.