Russo M, et al. - Study authors attempted to compare clinical and pathological characteristics at diagnosis with patient long-term outcomes as well as to assess ongoing risk stratifications in a large series of paediatric differentiated thyroid cancers (DTC). For this retrospective analysis, the clinical and pathological prognostic factors of one hundred twenty-four paediatric patients with DTC (age at diagnosis <19 years) followed up for 10.4 ± 8.4 years. Data reported that paediatric patients with DTC show an excellent response to treatment and often a favourable outcome in spite of the aggressive presentations at diagnosis. They suggested that node metastases (N1b) status should be considered a strong predictor of persistent/recurrent disease which, as in adults, was better predicted by ongoing risk stratification.