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Differential prevalence and demographic and clinical correlates of antidepressant use in American bipolar I vs bipolar II disorder patients

Journal of Affective Disorders Mar 11, 2018

Hooshmand F, et al. - Due to questionable efficacy/psychiatric tolerability, antidepressant use is controversial in bipolar disorder (BD). Researchers here assessd correlates of antidepressant use in bipolar I/II disorder patients. They observed higher antidepressant use in BD II vs BD I patients. In addition, antidepressant use was observed to be associated with markers of heightened illness severity in both BD I and BD II patients.
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