Sugiura T, et al. - Researchers designed this study to assess the effect of central blood pressure (BP), which reflects cardiac load rather than peripheral BP, on serum concentrations of high-sensitivity cardiac troponin I (hs-cTnI) in subjects with or without increased arterial stiffness. They observed that with increasing brachial and central BP, circulating levels of hs-cTnI increased. However, the central BP was found to have a greater effect in subjects with higher radial augmentation index. Thereby suggesting that central BP could be having a strong effect on silent myocardial damage, assessed as increased circulating hs-cTnI. This was particularly evident in subjects with increased arterial stiffness.