Song C, et al. - Sixty-two patients with nasopharyngeal carcinoma (NPC) and 39 patients with nasopharyngeal lymphoma (NPL) who underwent dynamic contrast-enhanced MRI (DCE-MRI) and readout-segmented diffusion-weighted imaging (RESOLVE-DWI) examinations were assessed by the researchers in order to investigate the benefit of DCE-MRI and RESOLVE-DWI in the distinguishing NPC and NPL. In patients with NPC, the most prevalent time signal–intensity curve was type III (n = 26) whereas in patients with NPL the majority of the curves were types I (n = 14) and II (n = 19). Between NPCs and NPLs, time to peak (TTP), enhancement peak (EP), maximum contrast enhancement ratio (MCER), apparent diffusion coefficient (ADC), and relative ADC (rADC) were statistically markedly different. Among these factors, followed by rADC, TTP, MCER, and EP, ADC exhibited the most reliable diagnostic performance. Furthermore, in comparison with TTP, MCER, and EP each alone, the diagnostic effectiveness of the combined DCE-MRI parameters was greater. The maximum diagnostic effectiveness was shown by the combination of all DCE-MRI and DWI parameters together. Amongst keratinizing NPC and non-keratinizing NPC or amongst NK/T lymphoma and diffuse large B cell lymphoma, the parameters did not vary significantly. Hence, DCE-MRI and RESOLVE-DWI were concluded to be efficient in distinguishing NPC from NPL.