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Differential diagnosis of nasopharyngeal carcinoma and nasopharyngeal lymphoma based on DCE-MRI and RESOLVE-DWI

European Radiology Dec 08, 2019

Song C, Cheng P, Cheng J, et al. - Sixty-two people with nasopharyngeal carcinoma (NPC) and 39 with nasopharyngeal lymphoma (NPL) who underwent dynamic contrast-enhanced MRI (DCE-MRI) and readout-segmented diffusion-weighted imaging (RESOLVE-DWI) examinations were assessed in order to investigate the utility of DCE-MRI and RESOLVE-DWI in the distinction of NPC and NPL. The most frequent time signal–intensity curve was type III in people with NPC (n = 26), while the preponderance of the curves were types I (n = 14) and II (n = 19) in individuals with NPL. Moreover, the combination of all DCE-MRI and DWI parameters together showed the greatest diagnostic competence. Nonetheless, between keratinizing NPC and non-keratinising NPC or between NK/T lymphoma and diffuse large B cell lymphoma, none of the parameters was significantly distinctive. Thus, in distinguishing NPC from NPL, DCE-MRI and RESOLVE-DWI are efficient.
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