Kloth C, et al. – The physicians conducted this work to determine the diagnostic aid of computed tomography (CT) features for the differentiation of active alveolitis and fibrosis using a CT texture analysis (CTTA) prototype and CT densitometry in patients with systemic sclerosis (SSc) using ancillary high–resolution computed tomography (HRCT) features and their longitudinal course as standard of reference. It was considered that CT texture analysis parameters are significantly different in active alveolitis vs. fibrosis in patients with systemic sclerosis and may be useful for differentiation of these two entities.