Østergaard L, Smerup MH, Iversen K, et al. - In cases with infective endocarditis (IE), surgery may result in improvement in survival and reduction in complications, however, the balance between benefit and harm is difficult and may be closely linked with age and type of surgical intervention. Researchers here investigated mortality in patients undergoing surgery for IE by age and type of left-sided surgical intervention. By crosslinking nationwide Danish registries, they identified 1,767 patients with IE undergoing surgery for inclusion in this study; of these, 735 patients were < 60 years (24.1% female), 766 patients were 60–75 years (25.8% female) of age, and 266 patients were ≥ 75 years (36.1% female). In patients undergoing surgery for IE, significant increase in mortality was observed with age; 1 in 5 died above age 75 years. Further augmentation of mortality was noted in correlation with mitral valve surgery and multiple valve interventions. .