Jiang H, et al. - In this meta-analysis of randomized controlled trials and cohort studies, researchers investigated the relation of dietary vitamins and carotenoids with the risk of age-related cataract (ARC). They used generalized least-squares trend estimation to calculate the dose-response relations. They observed a reduction in ARC risk by 26% for every 10-mg/d increase in lutein/zeaxanthin consumption. They also noted a reduction in ARC risk by 18% for each 500-mg/d increase in vitamin C intake, an 8% reduction for each 5-mg/d increase in β-carotene consumption, and a 6% reduction for every 5-mg/d increase in vitamin A intake. They suggested that consumption of certain vitamins, such as vitamin A and vitamin C, could reduce the risk of ARC prevalence.