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Dietary omega polyunsaturated fatty acid intake and patient-reported outcomes in systemic lupus erythematosus: The Michigan Lupus Epidemiology & Surveillance (MILES) Program

Arthritis Care & Research May 17, 2019

Charoenwoodhipong P, et al. - Researchers investigated how dietary intake of omega-3 (n-3; generally anti-inflammatory) and omega-6 (n-6; generally pro-inflammatory) fatty acids are associated with patient-reported outcomes in systemic lupus erythematosus (SLE). From the population-based Michigan Lupus Epidemiology & Surveillance (MILES) Cohort, they analyzed 456 SLE cases; among these, 425 (93.2%) were female, 207 (45.4%) were black, and mean age was 52.9±12.3 years. Outcomes revealed a favorabe association of higher dietary intake of n-3 fatty acids, and lower n-6:n-3 ratios, with patient-reported outcomes in SLE, particularly self-reported lupus activity and sleep quality.
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