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Diet quality and incident chronic kidney disease in the general population: The Lifelines cohort study

Clinical Nutrition Aug 11, 2021

Cai Q, Dekker LH, Vinke PC, et al. - In the general population, a lower risk of incident chronic kidney disease (CKD) or ≥20% eGFR decline was observed in relation to higher adherence to a high-quality diet.

  • Data were obtained from a prospective general population-based Lifelines cohort in the Northern Netherlands.

  • Diet quality was determined using the Lifelines Diet Score (LLDS).

  • Of 78,346 participants free of CKD at baseline, total 2,071 (2.6%) suffered CKD and 7,611 (9.7%) experienced a ≥20% eGFR decline.

  • A lower risk of incident CKD and ≥20% eGFR decline was evident in the highest tertile of LLDS vs the lowest tertile.

  • Similar dose-response links were noted in continuous LLDS.

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