Marques NR, et al. - Since identifying fluid responsiveness is critical to optimizing perfusion while preventing fluid overload, researchers performed this prospective observational study to investigate whether reduced ventricular compliance measured using transesophageal echocardiography results in decreased fluid responsiveness after a fluid bolus in 29 patients undergoing elective coronary revascularization. The intervention involved the infusion of albumin 5%, 7 mL/kg, over 10 minutes to characterize fluid responders (>15% increase in stroke volume) (n=15) from nonresponders (n=14). They evaluated left ventricular (LV) compliance at baseline and after albumin infusion. Findings revealed the presence of normal LV compliance and lower PVP at baseline in fluid responders, whereas, reduced LV compliance, which worsened after fluid bolus, was detected in nonresponders. They concluded that for predicting fluid responsiveness, E/e,’ may have more utility than PVP as a clinical index.