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Diaphragm disease in advanced ovarian cancer: Predictability of pre-operative imaging and safety of surgical intervention

European Journal of Obstetrics & Gynecology and Reproductive Biology May 24, 2018

Pounds R, et al. - Researchers sought to establish the positive predictive values of pre-operative identification with CT imaging of metastatic diaphragm disease in surgically managed cases of advanced ovarian cancer (AOC). Additionally, they assessed the post-operative morbidity and survival following diaphragmatic surgical intervention at the Pan-Birmingham Gynaecological Cancer Centre, UK between 1 August 2007 and 29 February 2016. Findings revealed frequent discovery of the diaphragmatic disease in AOC, however, its detection in pre-operative assessment with CT imaging seemed not reliably accurate. Therefore, they recommend considering all patients with AOC for diaphragm surgery. Their operation should be undertaken in cancer centres with adequate expertise in upper abdominal surgery. Partial muscle resection should be performed in case of suspicion of diaphragm muscle invasion during diaphragmatic peritonectomy. The surgical removal of diaphragmatic disease was identified not significantly increasing surgical morbidity.
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