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Diagnostic value of whole body diffusion-weighted MRI compared to computed tomography for pre-operative assessment of ovarian cancer

European Journal of Cancer Sep 01, 2017

Michielsen K et al. - In the current study, it was shown that WB-DWI/MRI was superior to CT for primary tumour characterisation, staging, and prediction of incomplete resection in patients suspected to have ovarian cancer.

Methods
161 patients underwent 3 T WB-DWI/MRI and contrast-enhanced CT to assess ovarian masses.

Results
WB-DWI/MRI had higher accuracy than CT (93% vs. 82%) in confirming the malignant nature of an ovarian mass.
WB-DWI/MRI correctly identified 26 of 32 cancers of non-ovarian origin compared to 10/32 for CT.
WB-DWI/MRI assigned more ovarian carcinoma patients to the correct FIGO stage (87%) compared with CT (35%).
WB-DWI/MRI had higher sensitivity (94% vs. 66%), specificity (97.7% vs. 77.3%), and accuracy (95.7% vs. 71.3%) in predicting incomplete resection compared to CT. 

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