Xia YR, et al. - This study was undertaken to investigate systematically the overall diagnostic value of urinary monocyte chemoattractant protein-1 (uMCP-1) in systemic lupus erythematosus (SLE) patients with active lupus nephritis (LN). Researchers retrieved articles from PubMed, Web of Science, EMBASE and Cochrane Library up to 5 November 2019. They applied the Quality Assessment of Diagnostic Accuracy Studies-2 tool to analyze study quality. This meta-analyses included a total of seven original studies recruiting a total of 521 individuals. The results of this this study suggested that, as a non-invasive biomarker, uMCP-1 has high diagnostic accuracy for active LN.