Rothman RK, et al. - The aim of this study is to ascertain the frequency of finding a primary cancer on CT of the chest, abdomen, and pelvis (CT CAP). Researchers searched a large academic hospital imaging database for cases of new intracranial lesions with subsequent CT CAP conducted for metastatic workup. A total of 287 were recruited in these analyses. In individuals with newly identified intraaxial and extra-axial brain lesions, the frequency of primary neoplasms diagnosed in the chest vs abdominal and pelvic portions of CT scans was ascertained. They noted lesion characteristics including size, number, and the presence of enhancement and hemorrhage. Ancillary signs of an abdominopelvic neoplasm were also reported. The study found that CTC is warranted in individuals with newly discovered brain lesions, but CTAP is unlikely to be beneficial in patients without ancillary signs of abdominopelvic neoplasm.