Diagnostic testing for Legionnaires' disease
Annals of Clinical Microbiology and Antimicrobials Sep 16, 2017
Pierre DM, et al. - Researchers here focused on diagnostic testing for Legionnaires disease. They identified the urinary antigen test as highly accurate for L. pneumophila serogroup 1, however other diagnostic tests should also be utilized in conjunction with the urinary antigen as many other Legionella species and serogroups seemed pathogenic. Culturing of patient specimens proved the gold standard for diagnosis of Legionnaires disease. Molecular tests seemed to provide much more rapid results in comparison to culture, however, in view of their lower sensitivity and specificity in comparison to culturing, these tests should not be a primary diagnostic tool. They recommended all laboratories to develop the ability to culture patient specimens in-house with the selective media to provide targeted antibacterial agent therapy.
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