Masuda-Kuroki K, et al. - Investigators estimated the histopathology of 11 palmoplantar pustulosis (PPP) and 6 pompholyx cases to analyze the histopathological characteristics of PPP and pompholyx to differentiate between these 2 disorders. They divided PPP cases into 3 phases ie, vesicle, pustulovesicule, and pustule whereas pompholyx cases into 2 phases ie, vesicle and pustule. They concluded histopathological findings of "vesicles without spongiosis" and "microabscess on the edges of vesicles" as the impact points for the differential diagnosis between PPP and pompholyx.