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Diagnostic and prognostic utility of computed tomography perfusion imaging in posterior circulation acute ischemic stroke: A systematic review and meta-analysis

European Journal of Neurology Jun 16, 2021

Katyal A, Calic Z, Killingsworth M, et al. - In this systematic review and meta-analysis, researchers sought to examine the diagnostic and prognostic capability of computed tomography perfusion (CTP) in acute ischemic posterior circulation stroke (PCS). The following studies were involved: patients aged 18 years or above; patients diagnosed with PCS; and studies with good methodological design. Out of 14 studies involved, a meta-analysis examining diagnostic accuracy of CTP was conducted on nine studies. CTP has limited diagnostic utility in acute ischemic PCS, despite having higher diagnostic sensitivity but lower diagnostic specificity than non-contrast computed tomography. More prospective trials are needed to validate the prognostic value of CTP-derived parameters in PCS.

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