Singh P, et al. - In this study, investigators examined data to research the overall diagnostic accuracy of the point of care tests (POCTs) for the diagnosis of celiac disease (CD). They used the Bivariate random-effect model to display the summary assessments of sensitivities as well as specificities along with 95% confidence regions. Using the quality assessment of diagnostic accuracy studies-2 tool, they evaluated the methodologic quality. They noted the respective 94.0% and 94.4% of the pooled sensitivity and specificity of all POCTs (based on tTG or DGP or tTG+Anti-gliadin antibodies) for diagnosing CD. They also noticed the pooled positive and negative likelihood ratios for POCTs, 16.7 and 0.06, respectively. The pooled sensitivity and specificity for IgA-tTG-based POCTs were reported 90.5% and 94.8%, respectively. They overall suggested the use of POCTs to screen for CD, particularly in regions with limited access to laboratory-based testing.