Mortezavi A, et al. - The diagnostic accuracy of multiparametric magnetic resonance imaging (mpMRI) and mpMRI / transrectal ultrasound (TRUS) fusion-guided targeted biopsy (FTB) against transperineal template saturation prostate biopsy (TTSPB) was evaluated by the researchers for the detection of prostate cancer (PCa). Due to a substantial number of false-negative cases with clinically significant PCa (csPCa), mpMRI alone ought not to be used as a triage test. In the diagnostic pathway of PCa, systematic biopsy outperformed fusion-guided targeted biopsy and hence remained crucial.