Lian MJ, et al. - Researchers investigated the performance of γ-glutamyl transpeptidase-to-platelet ratio (GPR) for diagnosing hepatitis B virus (HBV)-related significant fibrosis, severe fibrosis, and cirrhosis in this systematic review. Performing a comprehensive literature search of PubMed, Web of Science, and EMBASE, they incorporated 10 studies including 5882 patients with HBV infection underwent liver biopsy. Outcomes suggest that for predicting HBV-related significant fibrosis, severe fibrosis, and cirrhosis, GPR has moderate diagnostic accuracy with areas under summary receiver operating characteristic curves of 0.733, 0.777, and 0.796, respectively.