Longo C, et al. – Researchers prospectively evaluated 127 study participants to determine the diagnostic accuracy of fluorescence confocal microscopy (FCM) vs frozen sections in margin assessment of basal cell carcinoma (BCC) in the head and neck area. Upon analysis, they investigators noted a sensitivity of 79.8% and specificity of 95.8% with positive predictive values (PPV), 80.5% and negative predictive values (NPV), 95.7% while calculating the performance of FCM vs frozen sections. They observed 24 cases, false positive, and 25 false negatives when 49 subjects were re-assessed. Overall, they confirmed a higher level of accuracy for FCM vs frozen section estimation in intraoperative BCC margin evaluation during Mohs surgery.