Zhang H, Sun X, Xin P, et al. - Via this meta-analysis, researcher aimed to ascertain the diagnostic accuracy of D-dimer in periprosthetic joint infection (PJI). From PubMed, Embase, Web of Science, and Cochrane Library (from database establishment to April 2020), they included a total of 9 studies involving 1,592 patients. For PJI diagnosis, D-dimer was noted to have pooled sensitivity and specificity of 0.82 and 0.73, respectively. Findings suggest the promising value of D-dimer as a biomarker for the diagnosis of PJI, which should be employed in combination with other biomarkers or as an adjunct to other diagnostic methods to increase diagnostic performance.