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Diagnosis of vertebral deformities on chest CT and DXA compared to routine lateral thoracic spine X-ray

Osteoporosis International Feb 17, 2018

van Dort MJ, et al. - This trial aimed to evaluate the level of agreement of X-ray, CT and absorptiometry (DXA) and CT in the diagnosis of vertebral deformities from T4 to L1 in the case of chronic obstructive pulmonary disease (COPD) patients. Findings revealed that with all three imaging modalities, reproducibility of height measurements of vertebrae was excellent. In COPD patients, the diagnostic performance of CT [positive predictive value (PPV) 79–82%; negative predictive value (NPV) 90–93%], and to a slightly lesser extent of DXA (PPV 73–77%; NPV 80–89%) on subject level, indicated that these imaging techniques could be used for opportunistic screening of vertebral deformities.
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