Tellum T, et al. - Via a single-center, prospective observational study that consecutively recruited 93 premenopausal women who suffered from a benign gynecological condition, from September 2014 to August 2016, the researchers determined the diagnostic exactness of a junctional zone (JZ) thickness of ≥ 12 mm and morphological features of the JZ in magnetic resonance imaging for the diagnosis of adenomyosis in a premenopausal study population. Fifty-seven (61%) women got adenomyosis confirmed by histopathology. No positive association of junctional zone thickness (JZ_max) with adenomyosis diagnosis was found with no difference among those with and without adenomyosis and a cutoff of JZ_max ≥ 12 mm. Among the assessed signs, the best correlation of the presence of an irregular JZ with adenomyosis was ascertained. Hence, in the present premenopausal study population, JZ_max had no association with adenomyosis, however, direct signs of adenomyosis such as irregularities of the JZ gave a great diagnostic exactness.