Avanesov M, et al. – This work was intended to define these patients applying clinical, radiological and mortality data, and to assess the group of patients who need contrast–enhanced computed tomography (CECT). Physicians observed that 27% of all patients with acute pancreatitis (AP) presented without threefold increase of lipase levels. Therefore, they would be underdiagnosed without confirming contrast–enhanced computed tomography, which revealed significantly lower counts of pleural effusions and ascites. The data indicated that male patients with recurrent attacks (RAP) were observed significantly more often among the Lip– group. Hence, they would benefit the most from CECT for diagnosing AP.