Diabetes mellitus among adult survivors of childhood acute lymphoblastic leukemia: A report from the St. Jude lifetime cohort study
Cancer Nov 23, 2019
Williams HE, Howell CR, Chemaitilly W, et al. - Among clinically evaluated adult survivors of childhood acute lymphoblastic leukemia (ALL), researchers evaluated the prevalence and risk factors of diabetes mellitus. They analyzed information from survivors of ALL and community controls who were recruited in the St. Jude Lifetime Cohort Study between October 1, 2007, and June 30, 2016. Participants in the study were adults with ≥ 10 years of survival of childhood ALL and community controls who achieved clinical and laboratory evaluations. Of 1,360 eligible adults who were ≥ 10-year survivors of childhood ALL, a total of 1,044 finished the evaluations. T2DM was observed in nearly 7.47% of survivors and 3.80% of controls. Findings suggested that adult survivors of childhood ALL have a higher risk of T2DM. Adult survivors of childhood ALL who are of older age, with an overweight or obese BMI, and/or who developed drug-induced diabetes mellitus during treatment should be closely monitored during long-term follow-up for T2DM.
Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free or login with your existing account.
4 reasons why Doctors love M3 India
-
Exclusive Write-ups & Webinars by KOLs
-
Daily Quiz by specialty
-
Paid Market Research Surveys
-
Case discussions, News & Journals' summaries